One Inhaler Effective for Asthma Triple Therapy

For patients whose asthma is not well controlled, the addition of a long-acting muscarinic antagonist to the two-drug combination of an inhaled corticosteroid and a long-acting beta2 agonist in a single inhaler improves lung function and reduces asthma exacerbations, according to new research.

"This will have an impact on patients. For the first time, we've shown that triple therapy is effective with one inhaler," said investigator Johann Christian Virchow, MD, from Rostock Medical University in Germany.

"We know that even when you use the two-drug combination in high doses, we have patients whose asthma remains uncontrolled," he told Medscape Medical News. The third therapy offers a reduction in exacerbations, "especially for those with bronchoconstriction."

Virchow presented results from the triple-therapy study, also published online in the Lancet, here at the European Respiratory Society 2019 International Congress.

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